Anorexiants Drug – How does Anorexiants Works?
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Anorexiants Information – Side Effects, Uses and Benefits

Type of Drug:

Anorectic or anorexigenic drugs.

How the Drug Works:

Benzphetamine, diethylpropion, phendimetrazine, and phentermine ar central stimulants similar to amphetamine. These drugs reduce app title and may have other central or metabolic effects. Sibutramine pr longs the activity of central neurotransmitters.

Uses:

For the management of exogenous obesity as a short term adjunct (a flow weeks) in a regimen of weight reduction based on caloric restriction.

Precautions:

  • Psychological disturbances: Psychological disturbances have occurred in patients who received an anorexiant together with a restrictive diet.
  • Tolerance: Tolerance may develop within a few weeks. If tolerance develops, do not exceed the recommended dose to increase the effect; rather, discontinue the drug.
  • Pregnancy: There are no adequate and well-controlled studies in pregnant women. Anorexiant use in pregnancy is not recommended. Do not use benzphetamine in pregnant women.
  • Breastfeeding: Anorexiants are excreted in breast milk. It is not known if sibutramine appears in breast milk. Anorexiants are not recommended for nursing mothers. Consult your doctor before you begin breastfeeding.
  • Children: Safety and effectiveness of diethylpropion, phentermine, and sibutramine in children younger than 16 years of age have not been established. Phendimetrazine and benzphetamine are not recommended for use in children younger than 12 years of age.
  • Phentermine - Safety and effectiveness of Adipex-P have not been established. lonamin is not recommended in children younger than 16 years of age.
  • Elderly: Use sibutramine with caution in elderly patients.
  • Lab Tests:Lab tests  or exams may be required to monitor treatment. Tests may include blood pressure, pulse rate, and heart rhythm monitoring.

Drug Interactions:

Tell your doctor or pharmacist if you are taking or if you are planning to take any over-the-counter or prescription medications or dietary supplements with an anorexiant. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed. The following drugs and drug classes interact with anorexiants:

  • drugs that may raise blood pressure or increase heart rate (eg, certain decongestants;cough, cold, and allergyrine or pseudoephedrine)
  • MAOls (eg, phenelzine)
  • methyldopa (Aldomet)
  • serotonergic agents (eg, SSRls, medications that contains ephed-oids, lithium, tryptophan)
  • igraine drugs, certain opitricyclic antidepressants (eg, amitriptyline)

Side Effects:

Every drug is capable of producing side effects. Many anorexiant users experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy, and individual susceptibility. Possible side effects include:

  • Digestive Tract: Appetite changes; constipation; nausea; indigestion; vomiting; intestinal inflammation; stomach pain; diarrhea; dry mouth; gas.
  • Nervous System: Headache; migraine; sleeplessness; dizziness; nervousness; anxiety; depression; drowsiness; restlessness; general body discomfort; euphoria; agitation; jitteriness; emotional instability; abnormal involuntary movements; tremor; leg cramps; abnormal thinking.
  • Circulatory System: Increased heart rate; flushing; increased blood pressure; palpitations (pounding in the chest); chest pain; heart rhythm disturbances.
  • Respiratory System: Increased cough; shortness of breath.
  • Urinary and Reproductive Tract: Irregular vaginal bleeding; difficult or pain fulmination; changes in urinary frequency; impotence; changes in sex drive; increased breast size in males.
  • Skin: Rash; sweating; itching; hair loss; flushing.
  • Other: Abnormal lab tests; muscle, chest, neck, or back pain; joint pain or disorder; taste sensation changes; fever; fluid retention; double vision; weakness; blurred vision; pupil dilation.

Guidelines for Use:

  • If there is a patient package insert available with your prescription, read it before starting therapy and reread it each time your prescription is renewed.
  • Dosage is individualized. Take exactly as prescribed.
  • Do not change the dose or stop taking, unless directed by your doctor. These drugs can be addicting.
  • A single daily dose of benzphetamine is preferably given in the mid­morning or mid-afternoon, according to your eating habits. In an occasional patient, it may be desirable to avoid late afternoon administration.
  • Take diet hyperopic 1 hour before meals, and in mid-evening if needed to overcome night hunger. Take diet hyperopic controlled-release once daily at mid-morning.
  • Take immediate-release phendimetrazine 1 hour before meals. Take sustained-release phendimetrazine once daily in the morning, 30 to 60 minutes before the morning meal.
  • Take 15 or 37.5 mg phentermine as a single daily dose before break­fast or 10 to 14 hours before bedtime. Take Adipex-Pcapsules and tablets before breakfast or 1 to 2 hours after breakfast; the tablet dosage may be adjusted to the patient’s need.
  • Swallow loamingcapsules and all sustained-release products whole. Do not crush or chew.
  • Take sibutramine once daily with or without food.
  • If a dose is missed, take it as soon as possible. If several hours have passed or it is nearing time for the next dose, do not double the dose to catch up, unless advised to do so by your doctor. If more than one dose is missed or it is necessary to establish a new dosage schedule, contact your doctor or pharmacist.
  • Wait at least 2 weeks before starting treatment with an anorexiant after stopping MAOls and before starting MAOls after stopping an anorexiant.
  • Notify your doctor immediately if you experience rash, hives, or other allergic reactions; shortness of breath; chest pain; palpitations (pounding in the chest); nervousness; dizziness; fainting; swelling of the legs; pronounced dry mouth or constipation; deterioration of exercise tolerance; seizures; or sleeplessness.
  • Discontinue sibutramine and contact your doctor if seizures occur.
  • May cause drowsiness, dizziness, or blurred vision. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity.
  • Do not take other medications or dietary supplements without your doctor’s approval. This includes nonprescription medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems.
  • Avoid alcohol and other mental depressants (eg, narcotics, tranquilizers, antidepressants, hypnotics, antihistamines) while you are taking this medicine unless approved by your doctor.
  • Inform you doctor if you are pregnant, become pregnant, are planning to become pregnant, or if you are breastfeeding. Women of childbearing potential should use adequate contraception while taking these drugs.
  • Appetite suppressants are not a substitute for proper dieting. Lifestyle changes (eg, diet, exercise) are necessary to lose and then maintain weight loss.
  • Diabetic patients – Insulin requirements in diabetes mellitus may change in association with the use of anorexiants and the concomitant diet restrictions.
  • Avoid taking late in the day because of the possibility of sleeplessness.
  • The long-term effects of this medicine are unknown.
  • Lab tests or exams may be required to monitor treatment. Be sure to keep appointments.
  • Store at controlled room temperature (59° to 86°F) in a tightly closed container. Protect from heat and moisture.

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