Dipyridamole-aspirin Information – Side Effects, Uses and Benefits
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Dipyridamole-aspirin Guidelines for Using Dipyridamole-aspirin – Uses and Benefits

Type of Drug:

Combination anti platelet agent.

How the Dipyridamole-aspirin Works:

Aspirin and dipyridamole work together to prevent blood clots from forming by preventing platelets from clumping together. Platelets are parts of the blood that aid in clot formation.

Uses of Dipyridamole/aspirin:

To reduce the risk of stroke in patients who have had transient ischemia of the brain (TIAs) or complete ischemic stroke because of blood clots.


Do not use in the following situations: allergy to dipyridamole, aspirin, NSAIDs, or any of their ingredients asthma, nasal polyps, and rhinitis syndrome viral infections with or without fever, in children or teenagers

Use with caution in the following situations: alcohol use kidney disease bleeding abnormalities liver disease coronary artery disease low blood pressure gastrointestinal bleeding or peptic ulcer disease ulcers

  • Reye syndrome: There is a risk of Reye syndrome in children and teenagers when using aspirin in certain viral illnesses. Do not use in children or teenagers with viral infections with or without fever.
  • Pregnancy: There are no adequate and well-controlled studies in pregnant women. Use only when clearly needed and potential benefits out­weigh the possible risks to the fetus. Avoid the combination in the third trimester of pregnancy because of the aspirin component.
  • Breastfeeding: Dipyridamole and aspirin are excreted in breast milk.

Consult your doctor before you begin breastfeeding.

  • Children: Safety and effectiveness have not been established. This product is not recommended in children and teenagers because of the aspirin component.
  • Lab Test: lab tests may be required during treatment. Tests include liver and kidney function, blood counts, urine tests, and bleeding tests.

Drug Interactions:

Tell your doctor or pharmacist if you are taking or planning to take any over- the-counter or prescription medications or dietary supplements with this drug. Drug doses may need to be modified or a different drug pre­scribed. The following drugs and drug classes interact with this drug:

  • ACE inhibitors (eg, captopril)
  • Adenosine (Adenocard)
  • Anticoagulants (eg ibuprofen)
  • Ethotrexate (eg, Rheumatrex)
  • Diuretics (eg, furosemide)

Side Effects of Dipyridamole-aspirin:

Every drug is capable of producing side effects. Many patients experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy, and individual susceptibility. Possible side effects include:

  • Nervous System: Headache; forgetfulness; convulsions; confusion; drowsiness; dizziness; fainting; weakness.
  • Digestive Tract: Stomach pain; indigestion; heartburn; nausea; vomiting; diarrhea; coffee-ground or bloody vomit; appetite loss; dark or bloody stools; rectal bleeding; stomach bleeding; hemorrhoids.
  • Other: Unusual bleeding or bruising; nosebleed; anemia; joint, chest, muscle, or back pain; arthritis; rash; itching; hives; general body discomfort; coughing; upper respiratory tract infection; accidental injury; heart failure; abnormal tissue growth; fatigue.

Guidelines for Use:

  • Dosage is individualized. Take exactly as prescribed.
  • Do not stop taking or change the dose, unless instructed by your doctor.
  • Swallow capsules whole. Do not crush or chew.
  • Take with food if stomach upset occurs.
  • Do not interchange with individual components of aspirin and dipyridamole.
  • If a dose is missed, take it as soon as possible. If several hours have passed or it is nearing time for the next dose, do not double the dose to catch up, unless instructed by your doctor. If more than one dose is missed or it is necessary to establish a new dosage schedule, consult your doctor or pharmacist.
  • Patients who consume 3 or more alcoholic drinks every day are at a higher risk of gastrointestinal bleeding while taking aspirin.
  • Do not use in children or teenagers with viral infections with or without fever because of the risk of Reye syndrome associated with use of aspirin in certain viral illnesses.
  • Do not use other aspirin-containing products, unless instructed by your doctor.
  • Notify your doctor if you are pregnant, become pregnant, plan to become pregnant, or are breastfeeding.
  • Contact your doctor immediately if you experience signs and symptoms of unusual bleeding, gastrointestinal bleeding (eg, bloody vomit, dark tarry stools), or recurrent signs of stroke or TIA.
  • Notify your doctor if you experience bothersome side effects such as headache, indigestion, stomach pain, nausea, dizziness, or excessive bruising.
  • Do not take aspirin if you have a known allergy to NSAIDs, asthma, rhinitis, or nasal polyps.
  • Lab tests may be required to monitor treatment. Be sure to keep appointments.
  • Store at room temperature (59 to 86°F) in a dry pl ace.

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